Pedigrees for autosomal recessive traits

1. For rare traits, the pedigree usually involves mating between two unaffected heterozygotes and the production of one or more homozygous offspring.
2. The probability of an affected child from a mating of two heterozygotes is 25%
3. Two affected individuals usually produce offspring all of whom are affected
4. Males and females are at equal risk, since the trait is autosomal
5. In pedigrees involving rare traits, consanguinity is often involved

MiGRC – Autosomal Recessive

Autosomal recessive video

https://www.youtube.com/watch?v=yd5BEEbgkTU